Supplement
5-Amino-1MQ
SaveA small-molecule NNMT inhibitor studied in preclinical models for its effects on fat-cell metabolism and energy expenditure.
Quick verdict
Promising rodent data on fat metabolism but essentially zero published human trials. Treat as experimental.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Mouse studies show reduced adiposity and improved metabolic markers via NNMT inhibition. No peer-reviewed human efficacy or safety data exist as of early 2026.
Benefits
- May increase cellular energy expenditure in preclinical models
- Targets a novel metabolic pathway (NNMT)
- Under active investigation for obesity-related research
Dosage notes
No established human dose. Research-community forums cite 50–150 mg/day, but this is not clinically validated.
Side effects
- Unknown in humans
- Potential for off-target methylation effects
Who should be cautious
Uncharacterised long-term safety profile. Not approved by any regulatory body for human use.
What this page cannot tell you
All efficacy claims extrapolate from animal models. Purity of grey-market sources is uncertain.
Leaderboard scores
- Weight loss25
- Energy20
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