Nootropic
9-ME-BC
SaveA beta-carboline derivative that upregulates tyrosine hydroxylase and dopaminergic neurotrophic factors in rodent models. Human safety data is essentially absent.
Quick verdict
Intriguing preclinical dopaminergic profile, but no human trials exist and photosensitivity risk is a serious concern.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Rodent studies show increased dopamine synthesis and dendritic outgrowth in substantia nigra neurons. No published human pharmacokinetic or safety data.
Benefits
- Upregulates tyrosine hydroxylase in animal models
- Shows neurotrophic activity in dopaminergic neurons in vitro
Dosage notes
No validated human dosing exists. Online reports typically cite 10–30 mg/day but this is not evidence-based.
Side effects
- Severe photosensitivity
- Unknown long-term risks
Who should be cautious
Strongly photosensitizing — UV exposure during use could cause DNA damage. No human safety profile established.
What this page cannot tell you
All evidence is preclinical. The gap between rodent dopaminergic data and human cognitive outcomes is large.
Leaderboard scores
- Focus30
- Mood25
- Energy25
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