Peptide
Adiponectin
SaveAn adipocyte-secreted hormone involved in glucose regulation, fatty acid oxidation, and insulin sensitization.
Quick verdict
Well-characterized endogenous hormone with strong epidemiological links to metabolic health, but exogenous peptide therapy is not established.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Extensive observational and preclinical data. Low adiponectin correlates with metabolic syndrome. Therapeutic delivery remains a challenge.
Benefits
- Insulin-sensitizing effects in preclinical models
- Anti-inflammatory properties observed in vitro
- Cardioprotective associations in epidemiological data
Dosage notes
No validated exogenous human dosing exists.
Side effects
- Unknown for exogenous administration
- Theoretical hypoglycemia risk
Who should be cautious
Not available as an approved exogenous therapy. Recombinant forms are research-use only.
What this page cannot tell you
Observational associations are strong but do not prove exogenous supplementation is beneficial. Delivery and half-life issues persist.
Leaderboard scores
- Longevity30
- Weight loss25
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