Peptide
Adipotide
SaveA peptidomimetic that targets the vascular supply of adipose tissue by binding prohibitin on fat blood vessels, inducing fat-cell apoptosis.
Quick verdict
Showed dramatic fat loss in primate studies but caused significant renal toxicity. Human trials are very limited.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Primate data showed rapid fat loss with concurrent renal side effects. A small human pilot has been referenced but full data remain unpublished.
Benefits
- Rapid fat loss demonstrated in non-human primates
- Novel mechanism targeting adipose vasculature
Dosage notes
No validated human dosing. Primate studies used low mg/kg subcutaneous doses.
Side effects
- Renal tubular damage
- Dehydration
- Injection-site reactions
- Possible electrolyte imbalance
Who should be cautious
Renal toxicity observed in primates. Not approved for human use. Gray-market sourcing is risky.
What this page cannot tell you
Near-zero published human trial data. Animal efficacy came at the cost of kidney damage.
Leaderboard scores
- Weight loss35
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