Supplement
Allithiamine
SaveA lipid-soluble thiamine (vitamin B1) derivative originally isolated from garlic, offering improved bioavailability over water-soluble thiamine.
Quick verdict
A niche B1 form mainly relevant for people with thiamine deficiency or impaired absorption. Healthy individuals eating a balanced diet rarely need it.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Historical Japanese research demonstrated superior tissue uptake vs thiamine HCl. Clinical data are old and limited. Modern interest centres on benfotiamine instead.
Benefits
- Higher bioavailability than standard thiamine
- May support energy metabolism in deficient individuals
- Historical use in fatigue-related conditions
Dosage notes
50–100 mg/day is commonly cited, though clinical dose-ranging studies are limited.
Side effects
- Garlic-like body odour
- Mild GI upset
Who should be cautious
Garlic-like odour is common. Quality control varies between manufacturers.
What this page cannot tell you
Most modern research has shifted to benfotiamine. Head-to-head data with other lipid-soluble thiamines are sparse.
Leaderboard scores
- Energy38
- Focus30
Write a review
Sign in to write a review.