Peptide
Anserine
SaveA naturally occurring dipeptide (beta-alanyl-1-methylhistidine) found in skeletal muscle of birds and fish, with antioxidant and anti-glycation properties.
Quick verdict
Modest human trial data for uric acid reduction and anti-glycation. Generally safe as a dietary supplement but effects are mild.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Several small Japanese RCTs show modest uric-acid-lowering and anti-glycation effects. Often studied alongside carnosine.
Benefits
- Mild uric acid reduction in clinical trials
- Antioxidant and anti-glycation properties
- Generally recognized as safe in food-derived doses
Dosage notes
Human trials typically use 500–1000 mg/day of anserine/carnosine mixtures.
Side effects
- GI discomfort at high doses
- Fish/poultry allergen risk
Who should be cautious
Generally well tolerated. Sourced from fish/poultry, so allergen risk applies.
What this page cannot tell you
Human trials are small and mostly from a single research group. Effect sizes are modest.
Leaderboard scores
- Longevity30
- Recovery20
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