Supplement
Calcium alpha-ketoglutarate
SaveThe calcium salt of AKG used in the Rejuvant longevity trial, providing both AKG for Krebs-cycle support and a modest calcium contribution.
Quick verdict
The specific form tested in the biological-age trial. Whether it offers meaningful advantages over plain AKG beyond the calcium delivery is unknown.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
The Rejuvant trial (2021) used CaAKG at 1 g/day and reported biological age reversal by ~8 years on the TruMe DNA methylation clock over 7 months. Single trial, not independently replicated.
Benefits
- Specific form used in the Rejuvant biological-age trial
- Provides bioavailable AKG and calcium together
- Krebs-cycle support
Dosage notes
1000 mg/day was the trial dose. Often taken in the morning.
Side effects
- GI discomfort
- Bloating
Who should be cautious
Same AKG caveats apply. Added calcium may be undesirable for individuals already meeting calcium needs.
What this page cannot tell you
Biological-age clock changes are surrogate markers, not hard endpoints. Single unreplicated trial.
Leaderboard scores
- Longevity50
- Energy35
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