Peptide
CJC-1295
SaveA synthetic 30-amino-acid growth-hormone-releasing-hormone (GHRH) analog with extended half-life, used to stimulate endogenous GH secretion.
Quick verdict
Reliably raises GH and IGF-1 in human studies. Not FDA-approved; widely used off-label in anti-aging clinics.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Multiple human pharmacokinetic studies confirm sustained GH elevation. Limited long-term safety data. Typically refers to the version without DAC (Drug Affinity Complex).
Benefits
- Sustained increase in GH and IGF-1 levels
- Pulsatile GH release pattern preserved
- Used in combination with GH secretagogues in clinical protocols
Dosage notes
Typical clinic protocols: 100–300 mcg subcutaneously at bedtime. Often combined with ipamorelin.
Side effects
- Flushing
- Headache
- Water retention
- Injection-site reactions
- Transient numbness or tingling
Who should be cautious
Not FDA-approved. Long-term effects of chronic GH elevation are a concern. Avoid in individuals with active malignancies.
What this page cannot tell you
GH-axis stimulation is confirmed but clinical outcome data (body composition, aging) are limited.
Leaderboard scores
- Muscle40
- Recovery35
- Longevity25
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