Peptide
Cortexin
SaveA polypeptide preparation extracted from calf brain cortex, approved in Russia for neurological conditions including stroke, TBI, and cognitive impairment.
Quick verdict
Approved in Russia with several local clinical trials. Not recognized internationally; study quality is variable.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Multiple Russian clinical studies for stroke rehabilitation and pediatric neurology. Limited international publication or independent replication.
Benefits
- Approved in Russia for post-stroke cognitive support
- Used in pediatric neurology in CIS countries
- Generally well tolerated in published studies
Dosage notes
Russian clinical use: 10 mg IM daily for 10-day courses.
Side effects
- Injection-site pain
- Allergic reactions rare
- Headache
Who should be cautious
Animal-derived biological. Not approved outside Russia/CIS countries. Theoretical prion risk.
What this page cannot tell you
Studies are predominantly Russian with variable methodological quality. Not independently validated.
Leaderboard scores
- Memory28
- Focus22
- Recovery20
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