Supplement
FMN
SaveFlavin mononucleotide, an active coenzyme form of riboflavin involved in oxidoreductase reactions and mitochondrial electron transport chain complex I.
Quick verdict
Like FAD, this is a pre-activated B2 form. Niche utility for malabsorption or enzyme deficiency states. Most people convert riboflavin to FMN without difficulty.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
FMN is the precursor to FAD and a coenzyme for NADH dehydrogenase (complex I). Supplementation-specific data are very limited. Riboflavin studies apply by proxy since the body converts riboflavin → FMN → FAD.
Benefits
- Pre-activated riboflavin coenzyme
- Essential for mitochondrial complex I
- Bypasses the initial riboflavin-to-FMN conversion step
Dosage notes
10–50 mg/day. No well-established dose. Riboflavin at standard doses is sufficient for most individuals.
Side effects
- Yellow-orange urine (harmless)
- Generally very well-tolerated
Who should be cautious
No specific safety concerns. Stability of FMN supplements may vary.
What this page cannot tell you
Supplementing preformed FMN over standard riboflavin is justified only in rare metabolic conditions.
Leaderboard scores
- Energy28
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