Supplement
Gamma-Tocopherol
SaveA form of vitamin E found abundantly in nuts and seeds. It has anti-inflammatory and antioxidant properties distinct from alpha-tocopherol.
Quick verdict
Emerging evidence suggests anti-inflammatory benefits, but clinical trial data specific to gamma-tocopherol supplementation is limited.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Gamma-tocopherol traps reactive nitrogen species more effectively than alpha-tocopherol. Observational data links higher gamma-tocopherol levels with reduced cardiovascular and cancer risk, but interventional trials are scarce.
Benefits
- Traps reactive nitrogen species not addressed by alpha-tocopherol
- Anti-inflammatory properties in preclinical models
- May support cardiovascular health
Dosage notes
No established RDA. Supplemental doses typically range from 50-200 mg daily, often as part of mixed tocopherol formulas.
Side effects
- Generally well-tolerated
- Possible increased bleeding risk at high doses
Who should be cautious
High-dose alpha-tocopherol supplementation can deplete gamma-tocopherol. May interact with anticoagulants.
What this page cannot tell you
Most vitamin E trials used alpha-tocopherol only. Specific gamma-tocopherol supplementation trials are few and small.
Leaderboard scores
- Longevity30
- Immunity25
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