Peptide
GHK-Cu
SaveA naturally occurring copper-binding tripeptide (Gly-His-Lys-Cu) that declines with age, studied for wound healing, skin remodeling, hair growth, and anti-inflammatory effects.
Quick verdict
Among the better-studied cosmetic peptides. Solid in-vitro evidence for collagen synthesis and wound healing; clinical evidence is moderate, mostly for topical skin applications.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Dozens of in-vitro and animal studies. Several small human trials for wound healing and skin quality. Broad gene-expression effects documented in cell culture.
Benefits
- Stimulates collagen and glycosaminoglycan synthesis
- Promotes wound healing in clinical and preclinical studies
- Anti-inflammatory gene expression modulation in vitro
- Hair-growth-promoting effects in small studies
Dosage notes
Topical: serums at 1–3% concentration. Injectable community protocols: 1–2 mg subcutaneously (not validated).
Side effects
- Skin irritation with topical use
- Injection-site reactions
- Copper sensitivity in rare cases
Who should be cautious
Topical use is generally safe. Injectable use is off-label and not well studied for safety in humans.
What this page cannot tell you
Most clinical data are for topical use. Systemic injectable claims extrapolate from in-vitro and topical evidence.
Leaderboard scores
- Recovery40
- Longevity30
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