Peptide
Kisspeptin
SaveAn endogenous neuropeptide that potently stimulates GnRH release, playing a critical role in puberty onset and reproductive function.
Quick verdict
Well-studied in reproductive endocrinology with clinical trial data for infertility and hypogonadism. Potential as a diagnostic tool and IVF adjunct.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Multiple human studies confirm potent LH release. Clinical trials in IVF as an alternative to hCG trigger show reduced OHSS risk. Ongoing research in hypogonadism.
Benefits
- Potent LH/FSH stimulation in human studies
- Reduced ovarian hyperstimulation risk as IVF trigger
- Diagnostic potential for reproductive disorders
Dosage notes
Clinical trials: 1.6–12.8 nmol/kg IV or subcutaneously. Not commercially available for general use.
Side effects
- Injection-site reactions
- Headache
- Paradoxical suppression with continuous dosing
Who should be cautious
Investigational for most uses. Continuous administration can paradoxically suppress the reproductive axis.
What this page cannot tell you
Most promising as an IVF trigger alternative. Broader therapeutic applications remain under investigation.
Leaderboard scores
- Libido35
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