Peptide
Lunasin
SaveA 43-amino-acid soy-derived peptide with epigenetic and anti-inflammatory properties, studied for cholesterol reduction and cancer chemoprevention.
Quick verdict
Small human trials show LDL cholesterol reduction. Cancer-preventive claims are preclinical only. Available as a dietary supplement.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Several small human trials for cholesterol. In-vitro and animal cancer-prevention data. Epigenetic mechanism (histone acetylation inhibition) is well characterized in vitro.
Benefits
- LDL cholesterol reduction in small human trials
- Anti-inflammatory properties in vitro
- Soy-derived with generally safe dietary profile
Dosage notes
Supplement products typically provide 10–30 mg/day of lunasin-enriched soy extract.
Side effects
- Soy allergy risk
- Mild GI discomfort
- Potential estrogenic effects from soy matrix
Who should be cautious
Soy allergen. Cancer-preventive claims are not established in humans.
What this page cannot tell you
Cholesterol trials are small. Cancer data are preclinical. Bioavailability after oral ingestion is debated.
Leaderboard scores
- Longevity25
- Immunity15
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