Peptide
Melanotan 2
SaveA cyclic alpha-MSH analog that activates multiple melanocortin receptors, producing skin tanning, appetite suppression, and sexual arousal effects.
Quick verdict
Potent tanning and pro-sexual effects. Not approved anywhere. Carries significant risks including mole changes, nausea, and cardiovascular effects.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Human studies confirm melanogenic, anorectic, and pro-erectile effects. Safety profile is concerning. FDA has issued warnings against its use.
Benefits
- Effective skin tanning without UV exposure
- Pro-sexual effects documented in clinical studies
- Appetite suppression observed
Dosage notes
Community protocols: 0.25–1 mg subcutaneously. Loading phase followed by maintenance. Not medically validated.
Side effects
- Nausea
- Facial flushing
- Mole darkening and changes
- Unintended erections
- Increased blood pressure
- Fatigue
Who should be cautious
Not approved in any jurisdiction. Changes to existing moles raise melanoma screening concerns. Cardiovascular and CNS effects possible.
What this page cannot tell you
Broad melanocortin receptor activation produces multiple off-target effects. Long-term melanoma risk is unknown.
Leaderboard scores
- Libido50
- Weight loss20
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