Supplement
Papain
SavePapain is a proteolytic enzyme derived from papaya fruit used to support digestion and reduce inflammation.
Quick verdict
Useful as a digestive aid; anti-inflammatory evidence is preliminary but promising.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Most evidence comes from in-vitro and small clinical studies on wound healing and digestion. Larger trials are lacking.
Benefits
- Supports protein digestion
- May reduce inflammation and swelling
- Used traditionally for wound debridement
Dosage notes
Typical doses range from 500–1000 mg with meals. Potency is often measured in papain units (PU).
Side effects
- Throat irritation
- Allergic reactions in sensitive individuals
- GI discomfort at high doses
Who should be cautious
May cause allergic reactions in individuals with latex or papaya allergy. Can interact with blood-thinning medications.
What this page cannot tell you
Enzyme activity varies widely between products. Enteric coating may be necessary for systemic effects.
Leaderboard scores
- Recovery35
- Pain30
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