Supplement
Phylloquinone (Vitamin K1)
SavePhylloquinone (vitamin K1) is the plant-derived form of vitamin K, essential for blood clotting and bone metabolism.
Quick verdict
Well-established role in coagulation. Bone and cardiovascular benefits are better supported by K2 (MK-7).
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Essential nutrient with strong evidence for coagulation. Observational data links higher K1 intake to reduced fracture risk. K2 appears superior for extra-hepatic effects.
Benefits
- Essential for normal blood coagulation
- Supports bone mineralization
- Abundant in green leafy vegetables
Dosage notes
Adequate intake is 90–120 mcg daily. Supplemental doses typically 100–1000 mcg.
Side effects
- Very well tolerated
- No known toxicity from food or supplements
Who should be cautious
Contraindicated with warfarin and other vitamin K antagonists. Dosing must be consistent for those on anticoagulants.
What this page cannot tell you
K1 is preferentially used by the liver for clotting factors. K2 (MK-7) is generally preferred for bone and cardiovascular supplementation.
Leaderboard scores
- Longevity55
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