Supplement
Pterostilbene
SavePterostilbene is a dimethylated analog of resveratrol found in blueberries, with superior bioavailability and similar sirtuin-activating and antioxidant properties.
Quick verdict
Better absorbed than resveratrol with promising preclinical longevity and metabolic data. Human evidence is still developing.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Bioavailability roughly 4x that of resveratrol. Clinical trials show reductions in blood pressure and LDL cholesterol. Strong preclinical data on SIRT1 activation and neuroprotection.
Benefits
- Superior bioavailability compared to resveratrol
- May lower blood pressure
- Activates sirtuin pathways
- Antioxidant and anti-inflammatory
Dosage notes
50–250 mg daily. Often combined with resveratrol or grape seed extract.
Side effects
- Possible LDL increase at high doses
- Mild GI discomfort
Who should be cautious
May raise LDL in some individuals when used alone (without grape seed extract). Monitor lipids.
What this page cannot tell you
Most longevity and neuroprotective claims are extrapolated from animal studies.
Leaderboard scores
- Longevity55
- Memory35
- Mood30
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