Supplement
Pycnogenol
SavePycnogenol is a standardized extract of French maritime pine bark rich in procyanidins, with extensive clinical research on circulation, inflammation, and skin health.
Quick verdict
One of the better-studied plant extracts with evidence across multiple health domains including circulation, blood sugar, and skin aging.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Over 160 published studies including multiple RCTs. Evidence supports benefits for chronic venous insufficiency, blood glucose management, skin photoaging, and endothelial function.
Benefits
- Improves circulation and venous function
- Supports blood glucose regulation
- Reduces skin aging markers
- Anti-inflammatory and antioxidant
Dosage notes
50–200 mg daily. Most studies use 100–150 mg daily.
Side effects
- Mild GI discomfort
- Dizziness (rare)
- Headache
Who should be cautious
May enhance effects of antihypertensive and antidiabetic medications. Mild immunostimulatory effects.
What this page cannot tell you
Many studies are industry-funded. Generic pine bark extracts may not have identical composition.
Leaderboard scores
- Longevity55
- Recovery45
- Immunity40
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