Supplement
Pyruvic Acid
SavePyruvic acid (pyruvate) is a key intermediate in glycolysis studied for modest effects on body composition and exercise endurance.
Quick verdict
Weak and inconsistent evidence for fat loss and performance. High doses needed for marginal effects.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
A few small trials showed modest fat loss at very high doses (22–44 g/day). Exercise performance data is mixed. The required doses are impractical and cause GI distress.
Benefits
- Central metabolic intermediate
- May modestly enhance fat oxidation at high doses
- Potential ergogenic aid in theory
Dosage notes
Supplements typically provide 1–5 g, well below the 22–44 g used in positive trials.
Side effects
- GI distress (bloating, gas, diarrhea)
- Nausea at high doses
Who should be cautious
High doses cause significant GI side effects. No safety data for chronic high-dose use.
What this page cannot tell you
Effective doses in studies are far higher than typical supplement doses (1–5 g). Practical relevance is questionable.
Leaderboard scores
- Weight loss20
- Energy15
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