Supplement
Red Yeast Rice
SaveRed yeast rice contains monacolin K, which is chemically identical to lovastatin, and effectively lowers LDL cholesterol.
Quick verdict
Proven cholesterol-lowering effects, but essentially a natural statin with the same benefits and risks.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Multiple RCTs and meta-analyses confirm LDL reduction of 15–25%. A large Chinese trial (CCSPS) showed reduced cardiovascular events. Monacolin K content varies wildly between products.
Benefits
- Clinically proven to lower LDL cholesterol
- Reduced cardiovascular events in large trial
- Alternative for statin-intolerant patients (under supervision)
Dosage notes
Standardized to provide 3–10 mg monacolin K daily. Always choose citrinin-free products.
Side effects
- Muscle pain (same mechanism as statins)
- Liver enzyme elevation
- GI discomfort
- CoQ10 depletion
Who should be cautious
Carries the same risks as prescription statins: myopathy, liver enzyme elevation, rhabdomyolysis. May contain citrinin (a nephrotoxic mycotoxin) in poorly manufactured products.
What this page cannot tell you
Product quality is a major concern. Some products contain negligible monacolin K while others contain therapeutic amounts. Regulatory status varies by country.
Leaderboard scores
- Longevity65
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