Turkesterone

Social media hype far exceeds the evidence. No rigorous human RCTs confirm meaningful muscle-building effects.

A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.

Animal and in-vitro studies suggest protein synthesis activation via pathways distinct from androgens. However, no published peer-reviewed human RCTs demonstrate muscle or strength gains. A 2023 pilot study showed no significant effects on body composition.

• Theoretically anabolic via non-hormonal pathways
• Does not appear to suppress endogenous testosterone
• No banned substance classification

Marketed doses are 500–1000 mg daily of Ajuga turkestanica extract standardized to 10% turkesterone. Optimal dosing is unknown.

• GI discomfort and nausea
• Headache
• Product adulteration risk

Supplement market is plagued by adulteration and mislabeling. Many products contain little actual turkesterone.

Despite massive online popularity, the compound lacks basic human efficacy data. Product authenticity is a major concern.

• Muscle20