Supplement
Quercetin
SaveQuercetin is a widely distributed flavonoid with antioxidant, anti-inflammatory, and senolytic properties, found in onions, apples, and berries.
Quick verdict
Broad evidence for anti-inflammatory and immune-supporting effects. Emerging senolytic interest. Bioavailability is a key limitation.
Evidence score
A rough internal score reflecting quantity, quality, and consistency of human evidence. Not a clinical recommendation.
What the research shows
Clinical trials support reductions in blood pressure, upper respiratory infections, and inflammation markers. Senolytic activity (with dasatinib) shown in human trials. Bioavailability is poor without enhancement.
Benefits
- Anti-inflammatory and antioxidant
- May reduce upper respiratory infection duration
- Senolytic activity in combination protocols
- Supports cardiovascular health
Dosage notes
500–1000 mg daily. Bioavailability greatly improved with phytosome delivery or co-administration with vitamin C.
Side effects
- Headache
- GI discomfort
- Tingling sensations (rare)
Who should be cautious
May interact with certain antibiotics and cyclosporine. High doses may affect thyroid function.
What this page cannot tell you
Standard quercetin has low oral bioavailability (~2%). Phytosome or glycoside forms are significantly better absorbed.
Leaderboard scores
- Longevity60
- Immunity55
- Recovery40
Featured in protocols
- Longevity Stackadjunct
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