Goal picker
Match
Pick a goal. We'll rank compounds by our editorial score for that use case.
Choose a goal
Ranked for weight loss
- 92
Tirzepatide
A dual GLP-1/GIP receptor agonist (Mounjaro for diabetes, Zepbound for obesity) that demonstrated weight loss exceeding 20% in the SURMOUNT trials, surpassing GLP-1 monotherapy.
- 90
Semaglutide
A once-weekly GLP-1 receptor agonist FDA-approved for type 2 diabetes (Ozempic), obesity (Wegovy), and available in oral form (Rybelsus). Demonstrated cardiovascular and renal benefits.
- 85
CagriSema
A fixed-dose combination of cagrilintide (amylin analog) and semaglutide (GLP-1 RA) developed by Novo Nordisk, targeting weight loss through dual hormonal pathways.
- 82
Retatrutide
A triple agonist targeting GLP-1, GIP, and glucagon receptors, developed by Eli Lilly. Phase II data showed unprecedented weight loss exceeding 24% at 48 weeks.
- 72
Liraglutide
A once-daily GLP-1 receptor agonist FDA-approved for type 2 diabetes (Victoza, 1.8 mg) and obesity (Saxenda, 3.0 mg). Demonstrated cardiovascular benefit in the LEADER trial.
- 60
Cagrilintide
A long-acting acylated amylin analog developed by Novo Nordisk, designed to reduce appetite and food intake through amylin receptor signaling. Studied as monotherapy and in combination with semaglutide.
- 55
Berberine
An isoquinoline alkaloid from plants like goldenseal and barberry that activates AMPK, with glucose- and lipid-lowering effects comparable to some pharmaceuticals.
- 55
Dulaglutide
A once-weekly GLP-1 receptor agonist (brand name Trulicity) FDA-approved for type 2 diabetes with demonstrated cardiovascular benefit in the REWIND outcomes trial.
- 50
Tesamorelin
A synthetic GHRH analog (trans-3-hexenoic acid modified GRF 1-44) FDA-approved as Egrifta for the reduction of excess abdominal fat in HIV-associated lipodystrophy.
- 50
Whey Protein Isolate
Whey protein isolate is a highly filtered form of whey with 90%+ protein content, minimal lactose and fat, and the highest leucine content among common proteins.
- 50
GLP-1
Glucagon-like peptide-1, an endogenous incretin hormone secreted by intestinal L-cells in response to food intake. It stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and promotes satiety.