Goal picker

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Pick a goal. We'll rank compounds by our editorial score for that use case.

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Focus Anxiety Energy Memory Mood Stress Longevity Weight loss Muscle Recovery Libido Pain Immunity Sleep

Ranked for energy

Caffeine
The world's most widely consumed psychoactive substance, a methylxanthine that blocks adenosine receptors to promote wakefulness, focus, and physical performance.
85
Armodafinil
The R-enantiomer of modafinil, FDA-approved for narcolepsy, obstructive sleep apnea, and shift-work disorder. Longer plasma half-life than racemic modafinil.
82
Modafinil
A prescription eugeroic (wakefulness-promoting agent) FDA-approved for narcolepsy, shift-work disorder, and obstructive sleep apnea. Widely used off-label for cognitive enhancement.
80
Iron
An essential mineral required for oxygen transport, energy production, and numerous enzymatic reactions. Deficiency is the most common nutritional deficiency worldwide.
70
Iron Bisglycinate
A chelated form of iron bound to two glycine molecules, offering superior absorption and significantly fewer GI side effects compared to ferrous sulfate.
65
Vitamin B Complex
A comprehensive formula providing all eight B vitamins (B1, B2, B3, B5, B6, B7, B9, B12) essential for energy metabolism, nervous system function, and methylation.
65
Adrafinil
A prodrug of modafinil that is converted in the liver to its active metabolite. Originally developed in France for narcolepsy-related drowsiness.
65
Testosterone
The primary male sex hormone and an anabolic steroid. FDA-approved for testosterone replacement therapy (TRT) in hypogonadal men. Critical for muscle mass, bone density, libido, and mood.
65
Creatine monohydrate
The most extensively studied sports supplement in history. Increases phosphocreatine stores for rapid ATP regeneration, with emerging cognitive and neuroprotective benefits.
60
Vitamin B12 (Cobalamin)
Cobalamin is an essential vitamin required for DNA synthesis, red blood cell formation, and myelin maintenance, with deficiency common in vegans and older adults.
60
Phenylpiracetam
A phenylated piracetam derivative developed in Russia for cosmonauts. Provides both cognitive and physical stimulation. Banned by WADA as a performance enhancer.
60
Beetroot extract
Concentrated source of dietary nitrates that are converted to nitric oxide, reliably shown to improve exercise economy and modestly lower blood pressure.
58
Ginsenosides
A class of triterpene saponins found in Panax ginseng responsible for most of its adaptogenic, cognitive, and anti-fatigue effects.
55
Theacrine
Theacrine is a purine alkaloid structurally similar to caffeine found in kucha tea, providing energy and focus without habituation or tolerance.
55
Beta-alanine
A non-proteinogenic amino acid that increases intramuscular carnosine, buffering hydrogen ions during high-intensity exercise lasting 1–4 minutes.
50
CoQ10
Ubiquinone/ubiquinol, a lipid-soluble coenzyme essential for mitochondrial electron transport and a potent endogenous antioxidant. Levels decline with age and statin use.
50
Vitamin B1 (Thiamine)
Thiamine is an essential B vitamin required for glucose metabolism, nerve function, and the production of ATP via the pyruvate dehydrogenase complex.
50
Vitamin B3 (Niacin)
Niacin is an essential B vitamin and NAD+ precursor available in multiple forms (nicotinic acid, niacinamide, NR, NMN), each with distinct clinical profiles.
50
Cardarine (GW501516)
A PPARδ receptor agonist (not a true SARM) originally developed by GlaxoSmithKline for metabolic and cardiovascular disease. Commonly grouped with SARMs in the performance-enhancement community.
50
Panax ginseng
A classic Asian adaptogen standardized for ginsenosides and used for energy, cognition, and resilience.
50
Rhodiola rosea
A cold-climate adaptogen used for fatigue, stress resilience, and mental performance under load.
50